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‌Human lymphoid tissue section showing six channels from a 10-plex immunofluorescence stain, produced on Propath’s Lunaphore Comet platform.

CD4 green, CD8 orange, PD-1 red, PD-L1 magenta, FOXP3 white, DAPI blue

‌The very same section of human lymphoid tissue as previous image but now showing another five channels of the same 10-plex immunofluorescence stain.

CD20 green, CD3 red, CK magenta, Ki67 white, CD68 orange

‌Non-small-cell lung carcinoma  section with four colour fluorescent morphology stain.Image highlights epithelial tumour and immune infiltrate with region of interest and tissue segmentation overlays.

DNA, CD45, CD68, PanCK

‌Dual immunofluorescent staining of pSMAD (Cy5 fluorophore, orange) and a proprietary biomarker (FAM fluorophore, green) in pancreatic cancer tissue.

Strong positive pSMAD staining present in pancreatic islets, with some areas of co-localisation present indicated by bright yellow staining. DAPI nuclear stain is shown in blue.

‌GFAP (glial fibrillary acidic protein) staining of glial cells in the hippocampus.

Chromogenic DAB staining.

‌Chromogenic ISH staining of human NPY2 receptor in an animal model brain.

Only the human NPY2 receptor is specifically detected and not the endogenous NPY2 receptor.

‌Spatial protein and RNA analysis of a section of colorectal carcinoma using the NanoString GeoMx with IHC overlays.

Top left: GeoMx ROI selection for protein panel

Top right: GeoMx ROI selection for Whole Transcriptome RNA panel

Middle right:  Dual IHC stain for CD4 in purple and CD8 in yellow

Bottom right: IHC stain for PD-LI

‌Jones’ methenamine silver stain in mini-pig kidney demonstrating basement membranes.

‌Masson’s Trichrome stain with aniline blue counterstain of kidney, demonstrating collogen in blue/dark blue; muscle red blood cells and fibrin in red; and nuclei in blue/black.

‌H&E stain of skin and mammary gland, showing epidermis, dermis, hair follicles, fat cells and mammary gland.

‌H&E stain of testis/epididymis demonstrating testis (seminiferous tubules containing spermatocytes), interstitial Leydig cells; and epididymis: initial segment (dense tubular area above head), head (caput), corpus(middle), caput (tail).

‌Verhoff’s Van Gieson stain of aorta demonstrating aorta, tunica adventitia, tunica media, tunica intima, with collagen in red and elastic fibres in black.

‌H&E stain of eye demonstrating cornea, iris, lens, retina, choroid, optic nerve and Hardarian gland.