Propath partners with Navinci to offer automated protein–protein interaction detection using isPLA technology.
Propath has partnered with Navinci to offer automated protein–protein interaction detection using in-situ proximity ligation assay (isPLA) technology, expanding its capabilities in spatially resolved biology.
Understanding protein interactions within tissue context is critical for elucidating signalling pathways and disease mechanisms. The integration of isPLA enables direct visualisation and quantification of antigen proximity in situ in FFPE tissue sections, providing an additional layer of biological insight beyond expression profiling alone - measuring epitope colocation <40nm with spatial context.
Combined with Propath’s expertise in multiplex imaging and spatial analysis, this capability supports detailed investigation of cellular interactions, pathway activation, and target engagement. The partnership enhances Propath’s ability to deliver comprehensive, multi-layered datasets for both preclinical and clinical research applications.
Click here to learn more about Propath's services for in-situ proximity ligation assays.
