Nanostring GeoMX Digital Spacial Profiling

Cancer Transcriptome Atlas

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Cancer Transcriptome Atlas with NGS readout

The essential tool for spatial genomics in oncology

The GeoMx Cancer Transcriptome Atlas (CTA) is designed for comprehensive profiling of tumour biology, the tumour microenvironment, and the immune response.

Profile RNA expression of over 1,800 genes simultaneously with spatial resolution from distinct regions of interest with just a single tissue section.

The GeoMx CTA is designed to profile all aspects of tumour and tumour microenvironment biology

  • Profile the global immune response
  • Assess microenvironment immune activity
  • Quantify tumor reactivity to the immune response and therapeutic treatments
  • Measure clinically-derived gene sets including the 18-gene Tumor Inflammation Signature (TIS) known to be associated with response to PD-1/PD-L1 inhibitor pathway blockade, and the 50-gene Prediction Analysis of Microarray 50 signature (PAM50) known to be associated with breast cancer metastasis.

The GeoMX CTA at a glance

The GeoMx CTA panel spatially profiles targets critical to oncology and immuno-oncology research on the GeoMx Digital Spatial Profiler.

Comprehensive RNA content designed for cancer biology research in any tissue sample
Coverage of the immune response, tissue microenvironment, tumor biology, and genes from clinically relevant genes sets such as the Tumor Inflammation Signature and PAM50
Analysis of over 100 pathways to explore tumor biology
Compatible with RNAscope® and antibody morphology markers for tissue imaging
Customizable with up to 60 additional targets of interest
For use with next-generation sequencer (NGS) readout and compatible with DSP Data Center

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